Founded Year

2010

Stage

Debt - III | Alive

Total Raised

$855.77M

Last Raised

$50M | 3 mos ago

Mosaic Score
The Mosaic Score is an algorithm that measures the overall financial health and market potential of private companies.

-56 points in the past 30 days

About HeartFlow

HeartFlow provides a digital health service platform for heart disease diagnosis and treatments. It offers a non-invasive personalized cardiac test that provides unprecedented visualization of each patient’s coronary arteries, enabling physicians to create treatment plans for their patients. HeartFlow was formerly known as Cardiovascular Simulation. It was founded in 2010 and is based in Mountain View, California.

Headquarters Location

331 East Evelyn Avenue

Mountain View, California, 94041,

United States

650-241-1221

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HeartFlow's Product Videos

ESPs containing HeartFlow

The ESP matrix leverages data and analyst insight to identify and rank leading companies in a given technology landscape.

EXECUTION STRENGTH ➡MARKET STRENGTH ➡LEADERHIGHFLIEROUTPERFORMERCHALLENGER
Healthcare & Life Sciences / Monitoring, Imaging & Diagnostics Tech

The cardiac CT analytics platforms market is focused on improving the diagnosis and management of heart disease through the use of artificial intelligence and advanced imaging technologies. Companies in this market use tech to accurately detect and analyze features such as coronary artery stenosis, ventricular hypertrophy, and other anomalies that can be indicative of cardiac-related diseases. Tec…

HeartFlow named as Leader among 10 other companies, including Cleerly, Ultromics, and Idoven.

HeartFlow's Products & Differentiators

    HeartFlow FFRct Analysis

    The HeartFlow Analysis is a personalized cardiac test that leverages algorithms trained using deep learning and highly trained analysts to create a digital, personalized 3D model of the heart. The HeartFlow Analysis then uses powerful computer algorithms to solve millions of complex equations to simulate blood flow and provides FFRCT values along the coronary arteries. This information is used by physicians in evaluating the impact a blockage may be having on blood flow and determine the optimal course of treatment for each patient.

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Research containing HeartFlow

Get data-driven expert analysis from the CB Insights Intelligence Unit.

CB Insights Intelligence Analysts have mentioned HeartFlow in 3 CB Insights research briefs, most recently on Jan 5, 2024.

Expert Collections containing HeartFlow

Expert Collections are analyst-curated lists that highlight the companies you need to know in the most important technology spaces.

HeartFlow is included in 5 Expert Collections, including Unicorns- Billion Dollar Startups.

U

Unicorns- Billion Dollar Startups

1,277 items

T

Tech IPO Pipeline

568 items

D

Digital Health 50

150 items

The most promising digital health startups transforming the healthcare industry

D

Digital Health

11,398 items

The digital health collection includes vendors developing software, platforms, sensor & robotic hardware, health data infrastructure, and tech-enabled services in healthcare. The list excludes pureplay pharma/biopharma, sequencing instruments, gene editing, and assistive tech.

A

Artificial Intelligence

9,911 items

HeartFlow Patents

HeartFlow has filed 384 patents.

The 3 most popular patent topics include:

  • cardiology
  • heart diseases
  • cardiac arrhythmia
patents chart

Application Date

Grant Date

Title

Related Topics

Status

11/6/2023

2/11/2025

Medical imaging, Magnetic resonance imaging, Machine learning, Image processing, Health informatics

Grant

Application Date

11/6/2023

Grant Date

2/11/2025

Title

Related Topics

Medical imaging, Magnetic resonance imaging, Machine learning, Image processing, Health informatics

Status

Grant

Latest HeartFlow News

AI-Driven Diagnostics: The Future of Precision in Medical Imaging

Jun 20, 2025

Thomas Kluz, Managing Director at Niterra Venture During the past ten years, I’ve collaborated and invested in several innovative healthcare organizations, and I have realized that AI has extended beyond just being a supporting tool for medical purposes. It has proven, time after time, its capabilities in diagnostic applications. One of its most promising features is medical imaging, which could potentially drive operational speed rapidly and transform the entire future of medical capabilities in patient treatment. The healthcare industry is at its most crucial time for modernization. Professionals in radiology experience the highest level of workload burden within the medical care environment, as images are becoming harder and more complex for interpretation and analysis. A definite characteristic of modern imaging is the intense time pressure that X-rays, CT scans, or MRIs put the experts under due to the vast information that they need to review. Professionals are exposed to a large window of errors that could alter one’s health condition and treatment. According to the  Agency for Healthcare Research and Quality  (AHRQ), diagnostic errors contribute to approximately 10% of patient deaths and 6-17% of hospital adverse events. This is where technology, or AI in particular, can offer significant assistance. From Hype to Impact: Where AI Is Making a Difference AI systems that receive training from vast imaging databases can now perform nearly as well as human radiologists in identifying lung cancer alongside pneumonia, stroke, and COVID-19 abnormalities. It brings huge value to medical care that goes beyond basic detection capabilities. These tools can help: Assess critical patient cases according to severity level, allowing for prompt examination. Automatic processing capabilities that free medical staff to devote their attention to advanced medical cases, requiring more complex diagnostic decisions. Identify important irregularities that usually escape manual assessments, thus decreasing the number of diagnostic mistakes. Prediction technology enables clinicians to obtain better insights for implementing earlier interventions. AI functions as a resource magnifier to enhance high-end diagnostic abilities in healthcare facilities located in remote locations or low-resourced geographic areas, where radiology specialists do not exist. A New Layer of Clinical Intelligence AI advancements in imaging serve two main purposes: optimization and medical practice support, thus allowing for better data integration from medical history, lab results, gene information, to real-time vital signs. Hence, we can expect AI to detect a tumor while simultaneously making predictions about future behaviors of tumors, resulting in suggesting the most optimal treatments and patient-related outcomes. This capability will represent the initial stage of personalized diagnosis as it brings specific information together with real-time monitoring to shape healthcare decisions. The Investment Case for AI Diagnostics As a venture capitalist, I find the AI diagnostic opportunity especially appealing. According to  Grand View Research , the global AI in medical imaging market is expected to grow at a compound annual growth rate of 34.8% from 2024 to 2030 to reach USD 8.18 billion by 2030. Not only will we experience faster technological progress, but we can also limit our mistakes and inefficiencies. The future with AI is looking at overall better patient outcomes and long-term cost savings. The best approach to reduce chronic disease involves early detection, followed by proper medical intervention. With AI, we will be able to detect any factors sooner, preventing late responses and prolonged conditions that could lead to permanent states by responding urgently to direct medical professionals. For investors, AI diagnostic tools present a valuable opportunity as the healthcare sector has always suffered from high costs and insufficient service delivery. I believe this will be one of the key terms we will hear in the next few years within the industry. This category of startups has already demonstrated high levels of success in their operations. Aidoc, Zebra Medical Vision, and HeartFlow use AI to transform how healthcare providers identify and handle stroke cases, heart issues, and cancer diagnoses. The common ground among these companies lies in their solid clinical background and their provider network alliances, together with their extensive validation research, which investors should prioritize. The Challenges Ahead Innovation, within a highly restricted industry like healthcare, has always been under scrutiny. AI startup companies need to handle multiple complex barriers, including securing regulatory permissions, while building trust with providers, managing reimbursement systems, and properly handling patient information. The vital matter of algorithmic bias remains a significant problem in this field. Without a high-quality training data set, no AI system could achieve its full potential despite the glamorous marketing. Ensuring that the datasets are under careful supervision for biases, accounting for race, gender, age, and geographic locations, is crucial in preventing care differences. The industry must not settle for an unfair and untransparent system that could easily harm its most vulnerable consumers. Building a Future We Can Trust AI-driven diagnostics face significant obstacles, but I strongly believe they will establish themselves as the backbone of present-day healthcare systems. The main question is not about whether AI will reshape medical imaging, but when we can implement its benefits for patients and healthcare providers. This revolution requires a collective effort from investors who understand the complexity of technology and regulations, healthcare providers who always strive for the best benefits of their patients, and startups with a commitment to developing a truthful technology that takes into account the patients’ and the caregivers’ needs. The role of AI in healthcare should be clear and transparent: an assistant, not a replacement. Our goal must be a system devoted to our people, with great technology and humanity. My healthcare career has focused on supporting revolutionary healthcare concepts, and I consider AI diagnostic systems to be among the most significant and powerful opportunities at the moment. I am honored to support this vision and this community. About Thomas Kluz Thomas Kluz is a distinguished venture capitalist with over a decade of experience. He’s the Managing Director of Venture Lab , where his investments focus on energy, mobility, and healthcare. With deep expertise in healthcare-focused venture capital, he has a proven track record of success with various organizations, such as Qualcomm Ventures and Providence Ventures.

HeartFlow Frequently Asked Questions (FAQ)

  • When was HeartFlow founded?

    HeartFlow was founded in 2010.

  • Where is HeartFlow's headquarters?

    HeartFlow's headquarters is located at 331 East Evelyn Avenue, Mountain View.

  • What is HeartFlow's latest funding round?

    HeartFlow's latest funding round is Debt - III.

  • How much did HeartFlow raise?

    HeartFlow raised a total of $855.77M.

  • Who are the investors of HeartFlow?

    Investors of HeartFlow include U.S. Venture Partners, Martis Capital, HealthCor Management, Wellington Management, Scottish Mortgage Investment Trust and 13 more.

  • Who are HeartFlow's competitors?

    Competitors of HeartFlow include MEDICAL IP, Cleerly, Caristo Diagnostics, Medipixel, Elucid and 7 more.

  • What products does HeartFlow offer?

    HeartFlow's products include HeartFlow FFRct Analysis.

  • Who are HeartFlow's customers?

    Customers of HeartFlow include Atrium Health.

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Compare HeartFlow to Competitors

C
Corcillum

Corcillum specializes in cardiovascular diagnostics and research within the healthcare technology sector. Its main offerings include a platform for medical image annotation, multi-physics modeling, and the development of digital coronary twins for personalized cardiovascular assessments. Corcillum serves the healthcare and medical research sectors with its solutions. It was founded in 2022 and is based in Adelaide, Australia.

Cleerly Logo
Cleerly

Cleerly is a digital healthcare company focused on the diagnosis and treatment of heart disease through its solutions in the cardiovascular care sector. The company offers a digital care platform that uses non-invasive CT imaging to identify and quantify atherosclerosis, enabling treatment plans for heart disease. Cleerly's technology aims to provide phenotyping of coronary artery disease, improving the accuracy of heart attack risk assessments and supporting clinical decision-making. It was founded in 2017 and is based in Denver, Colorado.

Caristo Diagnostics Logo
Caristo Diagnostics

Caristo Diagnostics specializes in cardiovascular diagnostic tools within the healthcare technology sector. The company enhances the accuracy of routine cardiac computed tomography scans by identifying coronary inflammation and other hidden cardiac issues, which improves the prediction of cardiovascular risk and aids in treatment decisions. Its technology is utilized in preventive screening, disease diagnosis, intervention planning, and clinical research. The company was founded in 2017 and is based in Oxford, United Kingdom.

Perspectum Logo
Perspectum

Perspectum provides imaging solutions within the healthcare industry and focuses on precision medicine. The company offers diagnostic tools that extract biomarkers from medical imaging to assist in the diagnosis and treatment of conditions, including liver disease, diabetes, and cancer. Perspectum's technology aims to help healthcare providers by offering data relevant to patient care. It was founded in 2012 and is based in Oxford, United Kingdom.

Elucid Logo
Elucid

Elucid specializes in advanced arterial analysis software within the healthcare technology sector. The company offers software that provides objective and quantitative assessment of arterial plaque, validated by histology, to aid in the diagnosis and treatment of cardiovascular diseases. Elucid's software is designed to support physicians, patients, and clinical researchers by improving the accuracy of non-invasive testing and enabling personalized care. It was founded in 2013 and is based in Boston, Massachusetts.

Resonance Health Logo
Resonance Health

Resonance Health is a MedTech company specializing in non-invasive medical imaging analysis and clinical trial services within the healthcare sector. The company offers a range of MRI-based products that provide quantitative assessments of liver and heart iron concentration, as well as automated AI-powered liver fat analysis, to aid in patient diagnosis and management. Resonance Health also provides clinical trial services, including standalone diagnostic imaging and central laboratory analysis. It was founded in 2000 and is based in Burswood, Western Australia.

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